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Court orders CVS to comply with the FTC’s PBM-related investigation

The Federal Trade Commission is continuing its investigation into anticompetitive PBM practices, with a new court order that will require CVS Health to share more requested documents about its PBM....

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Eikon raises $351M Series D, pipeline advances to Phase 3

One of biotech's best-funded startups has just raised a huge new round to take its lead drug into final-stage testing. On Wednesday, Eikon Therapeutics announced a $351 million Series D round, one of...

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Merck says Keytruda could be up next for IRA price cuts

Merck said its “once-in-a-lifetime” drug Keytruda could be subject to price reductions under the Inflation Reduction Act, which would lead to a decline in sales. It expects Keytruda to be chosen for ...

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Ginkgo uncertain over the future of US government funding, stock drops

Ginkgo Bioworks’ stock $DNA fell by around 13% premarket Wednesday after the company dampened its 2025 sales forecast. “We are being conservative with our revenue guidance in 2025 given uncertainty...

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Updated: Lilly joins Trump administration to announce $27B manufacturing...

WASHINGTON — Eli Lilly touted a huge new US manufacturing investment at an event on Wednesday, trotting out the news with a member of President Donald Trump’s cabinet as part of what has been a...

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Harbour BioMed inks deal up to $395M; ORIC refines plans for two drugs

Plus, news about Idorsia, Enveda, Zymeworks, BerGenBio and Ignota Labs: Harbour BioMed does another deal: The Shanghai-based biotech’s subsidiary, called HBM Alpha Therapeutics, inked a pact with an...

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Regeneron, two Chinese biotechs tout promise of their hearing loss gene...

Several small clinical trials have demonstrated that gene therapies have restored hearing in children with a rare form of genetic deafness. In an update at the Association for Research in...

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AstraZeneca’s SERD hits primary endpoint in late-stage trial, but first-line...

AstraZeneca wasn't expected to have data from the Phase 3 trial of its oral SERD until the second half of this year so the positive interim results that the UK drugmaker

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Regeneron shakes up accelerated approval plans for lymphoma bispecific

Regeneron is now expecting an accelerated approval decision this summer on its T cell engager for one form of lymphoma, while it's giving up on accelerated approval for a different form of the disease....

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Medicare spending on set of diabetes drugs skyrocketed — report

The use of a subset of common diabetes drugs skyrocketed in the US Medicare program over a five-year period ending in 2023, according to a new report from the HHS inspector general. The

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FDA meeting to pick next winter's flu shot is canceled

A meeting by a panel of science advisors to choose flu strains to include in a vaccine for next fall has been canceled on short notice, according to a member of the committee, raising concerns ...

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Sorriso Pharmaceuticals outlines Phase 1b ulcerative colitis data for oral...

Private startup Sorriso Pharmaceuticals laid out Phase 1b data at a medical conference last weekend as part of its effort to bring an oral antibody to market for IBD patients. The results come after...

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Kallyope quietly reports Phase 2 obesity data, begins mid-stage migraine trial

Kallyope, a New York City biotech that has raised about $480 million over the past decade, quietly released results of its Phase 2 study in obesity in ...

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Merck mulls new site in Delaware; Granules India buys peptide CDMO

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. Merck has received a $30 million strategic fund from the state of...

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Bayer CEO Bill Anderson previews 2025 turnaround plans

Something changed for Bill Anderson when he turned 50. He was ascending the ranks of Roche’s Genentech, but the Texas native felt like he was stuck in the same loop year after year. The company ...

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Hansoh ends collaboration with Silence; Vir hunts for HBV drug partner

Plus, news about Alopexx, Medigene, EpimAb and Belite Bio: Hansoh backs out of siRNA pact with Silence Therapeutics: The London-based biotech said Hansoh has decided not to ...

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Teladoc reports $1B net loss as it works to turn around its business

Teladoc wrapped up its financial year with a $1 billion net loss and disappointing results as the telehealth giant continues to work on its turnaround strategy. The net loss was in a big part due ...

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Verve is latest gene editing company to suffer setback, as Vertex walks away...

Verve Therapeutics has not escaped the doom that seems to be engulfing the gene editing sector of late. The company said Thursday that Vertex Pharmaceuticals handed back the rights to a ...

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OpenAI meets cancer care

Most healthcare organizations have been using AI for decidedly unglamorous tasks like documentation and billing. Now we’re starting to see how it could be used in clinical care. Color Health and OpenAI...

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Drug policy veteran at CMS to depart on Friday

John Coster, CMS' senior technical advisor for the Medicare drug rebate and negotiation group, told Endpoints News that he's leaving his agency on Friday. Coster, who has been at CMS for more than a...

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