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ITM aims to compete with Novartis after Phase 3 radiopharma win

ITM Isotope Technologies Munich plans to seek approval for its β-emitting radioligand in gastroenteropancreatic neuroendocrine tumors (GEP-NETs) following a Phase 3 success, the biotech said Tuesday....

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Atalanta gets $97M boost to take two siRNAs into clinic for rare neuro disorders

For five years, Atalanta Therapeutics operated with one investor. Now, F-Prime Capital is getting a bevy of financial support to propel two of the Boston biotech's RNAi drugs for rare neurological...

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Lantheus to buy radiopharma player Evergreen Theragnostics for $250M upfront 

In its latest move to expand its portfolio, Lantheus Holdings is spending $250 million upfront to buy radiopharma CDMO and diagnostics company Evergreen Theragnostics, which could also receive up to...

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Akero, 89bio disclose public offerings; BioAge drops Phase 2 obesity drug

Plus, news about Vigonvita Life Sciences and Lutris Pharma: For MASH developers, a race for cash: Akero Therapeutics aims to raise $300 million in an offering that was announced the same ...

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Biopharma execs split on RFK Jr. before confirmation hearing

Robert F. Kennedy Jr. will sit before a Senate committee on Wednesday and provide the first substantive glimpse into how he may run the nation's health department. Capitol Hill's questioning could...

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Leap Therapeutics treks toward pivotal study in colorectal cancer, drops...

Leap Therapeutics reported mixed results on Tuesday for an experimental treatment in gastric and colorectal cancer, announcing it is only moving forward with the latter indication. The biotech’s shares...

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What we know — and don’t know — about insurance denial rates

One insurance metric that we don’t often see showing up on earnings calls: the rate at which health plans issue denials. In the wake of UnitedHealthcare CEO Brian Thompson’s murder last month, a lot of...

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Semaglutide, tirzepatide compounder hit with FDA warning letter 

Compounding facility ProRx Pharmacy Network has received an FDA warning letter over issues with its semaglutide and tirzepatide production. The FDA uncovered several issues at ProRx’s facility in...

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Two February FDA adcomm meetings are delayed, canceled

President Donald Trump’s communications and travel freeze at HHS may be part of the reason an upcoming FDA advisory committee meeting has been delayed, and another one canceled. A Feb. 5 meeting on...

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Novo Nordisk asks Third Circuit to expedite IRA case

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Ozempic label expanded to include reduced risk of worsening kidney disease

The FDA on Tuesday broadened the label of Novo Nordisk's blockbuster diabetes drug Ozempic. The GLP-1 injectable can now also be marketed for the reduction in risk of worsening kidney disease ...

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AstraZeneca, Daiichi Sankyo bring Enhertu to HER2-ultralow setting

AstraZeneca and Daiichi Sankyo’s antibody-drug conjugate Enhertu is now approved to treat a new subset of breast cancer patients with very low levels of HER2 protein. The blockbuster drug has been...

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Lilly cuts mid-stage heart failure and chronic kidney drug

Eli Lilly is discontinuing a Phase 2 relaxin treatment candidate for heart failure and chronic kidney disease, a spokesperson for the company confirmed to Endpoints News. The drug, an under-the-skin...

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Judge allows Aurion Biotech's path to IPO despite Alcon objections

A Delaware judge issued a split ruling in a bizarre legal squabble over the IPO plans of Aurion Biotech, which should allow the cell therapy startup to go ahead with its public offering. The judge' ...

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Updated: Zentalis lays off 40% of staff, whittles down indications for WEE1...

Zentalis Pharmaceuticals is axing about 40% of its staff and refocusing its only pipeline candidate on a smaller group of ovarian cancer patients. The San Diego-based biotech had 168 full-time...

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Kennedy hearing updates: Trump HHS nominee faces Senate

Through a contentious three-and-a-half-hour hearing, Robert F. Kennedy Jr. emerged relatively unscathed as the Senate considers his nomination for HHS secretary. Democratic senators grilled Kennedy...

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Trump administration makes first comments on how it will run IRA drug...

The Trump administration said on Wednesday it will consider "opportunities to bring greater transparency” to the Medicare drug price negotiation process under the Inflation Reduction Act. With the...

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Curie.Bio has a new $340M fund; Layoffs at Benchling, I-Mab

Plus, news about Cullinan Therapeutics, Regulus and Imvax: Curie.Bio’s new $340M fund: The investment firm and biotech startup incubator disclosed the second seed fund on Wednesday. Curie.Bio generally...

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23andMe weighs a sale as cash dwindles

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Lonza looks to buy facilities and tech to boost service offerings

Lonza said Wednesday morning it is on the hunt for deals to increase its capacity and technology offerings, which comes after its revenues took a small hit last year and it recently revealed plans to ...

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